• Two connected transparent culture chambers into which a specific culture insert or membrane can be placed
• Bioreactor with several possibilities of media flow to adapt to different research protocols (air/liquid, liquid/liquid method...)
• Different insert sizes for 6, 12 or 24 wells
Two configurations:
• Tangential flow configuration: for the study of physiological barriers, the apical and basal poles are perfused by 2 independent flows parallel to the membrane.
• Perfusion flow configuration: for the 3D study, the flow lines passing vertically through the cells. Two types of configurations can be chosen.
Applications:
• Possibility of studying different cell types, or tissues from different organs (liver, intestine, lung, skin...) which can be interconnected by linking the LiveBoxes to evaluate the effects of their exchanges in the same environment
• 3D suspension cell culture, ALI method culture..
• Simulation of physiological barriers by creating an in vivo environment
• The starter kit includes everything needed to start the experiments: LB2 with clamp, porous membranes, tubes, connectors and mixing chambers
